Science and Research

The Science Behind Moducare

Moducare contains beta-sitosterol and beta-sitosterol glucoside in a clinically researched ratio of 100 to 1 shown to modulate the immune system. Human clinical research has been ongoing since the 1980s providing evidence that Moducare works to make a weak immune response stronger while dampening an overactive immune response. Moducare is in the elite category of extensively researched natural products.

Moducare’s unique blend of plant sterols and sterolins help promote a balanced immune system. Plant sterols and their glycosides, also known as phytosterolins, – are good fats that are present in fruits, vegetables, nuts, seeds, medicinal plants and some shellfish. Beta-sitosterol (BSS) and its glycoside (BSSG) are the most abundant of these plant sterols. BSS and BSSG, even at very low levels, have been shown to enhance the activity of various cells in the body that are recognized as having a positive impact on immune function. Specifically, these plant sterols and their sterolins can improve the balance of T-helper 1 to T-helper 2 cells, enhance cellular immunity, and down-regulate an overactive immune response. Moducare supplementation also helps maintain a normal ratio of the two adrenal hormones, cortisol and DHEA, which helps to buffer negative stress responses and control inflammation and autoimmunity.

Introduction to Moducare

For more than three decades, Professor Patrick Bouic has been running clinical studies of plant sterols and sterolins and their immune-modulating properties.

What is Moducare?

Moducare® is a clinically-researched, proprietary blend of plant sterols and sterolins in a 100:1 ratio. Moducare helps to support a healthy immune system balance.

Who Needs Moducare?

Moducare is available in a vegetarian capsule or grape-flavoured chewable tablet. For ages 5+.

Balance Don’t Boost

Why we should not boost our immune systems; instead, we want to have a balanced immun system.

Moducare and COVID Study

Professor Patrick Bouic discusses the initial findings of the effects of plant sterols and sterolins on viral infections.

Moducare and Stress

Professor Patrick Bouic discusses how Moducare helps to modulate the immune system in response to stress.

Summary of Research

Moducare’s blend of sterols and sterolins has been studied in clinical trials for the treatment of tuberculosis, marathon runners and immunosuppression, rheumatoid arthritis, allergic rhinitis, and benign prostatic hyperplasia.

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Healthy Living

A mixture of sterols and sterolins modulate the growth of estrogen-responsive breast cancer cells in vitro and in mice.

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Beta-Sitosterols

Beta-sitosterol activates Fas signaling in human breast cancer cells.

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Exercise-Induced Immune Suppression

The effects of beta-sitosterol (BSS) and beta-sitosterol glucoside (BSSG) mixture on selected immune parameters of marathon runners: Inhibition of post marathon immune suppression and inflammation.

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Rheumatoid Arthritis

Sterols and sterolins and their role in the control of rheumatoid arthritis.

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Allergies in Children

Clinical and laboratory changes in children with allergic rhinitis after 6 months of treatment with combination beta-sitosterol and beta-sitosterol glucoside.

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Moducare and Allergies

Allergies are a sign of an overactive immune system. Professor Patrick Bouic discusses how Moducare helps to support a healthy immune system balance for people with allergies.

Collagen and Moducare

Professor Patrick Bouic discusses the benefits of supplementing with collagen type 2 and Moducare for joint health.

HPV

A randomized trial of efficacy of beta-sitosterol and its glucoside as adjuvant to cryotherapy in the treatment of anogenital warts.

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Sterols and Sterolins

Analysis of steryl glucosides in foods and dietary supplements.

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Viral Infections

Immunomodulation in HIV/AIDS: The Tygerberg/Stellenbosch University Experience.

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FIV

Comparative changes in laboratory parameters of specified pathogen free (SPF) and non-specified pathogen free (non-SPF) laboratory cats infected with feline immunodeficiency virus (FIV).

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